Trial intelligence / Profile preview

CD27+CD21+ B-cell and IgA plasmablast dynamics in IgA nephropathy patients treated with Nefecon

ChiCTR2500115491Phase 4Not yet recruiting

Sponsor
Shenzhen Second People's Hospital
Start
Dec 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Drug Delivery Systems
Countries
1
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Overview

Phase 4, open-label, single-arm trial of nefecon in IgA nephropathy (IgAN), sponsored by Shenzhen Second People's Hospital. Primary endpoints: Percentage reduction in 24-hour proteinuria at 12 months versus baseline, Plasma galactose-deficient IgA1 and 3 more. Planned start Dec 2025; status: not yet recruiting.

02

Drugs

nefecon
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Conditions

IgA nephropathy (IgAN)

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