Trial intelligence / Profile preview

Phase II trial of Flonoltinib maleate vs ruxolitinib in intermediate/high‑risk myelofibrosis

ChiCTR2500115640Phase 2Completed

Sponsor
Institute of Hematology and Blood Transfusion
Start
Dec 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of flonoltinib in myelofibrosis (MF) (3 arms), sponsored by Institute of Hematology and Blood Transfusion. Primary endpoint: Proportion of subjects with ≥35% reduction in spleen volume vs baseline at Week 24 (IRC assessed). Started Dec 2025; status: completed.

02

Drugs

flonoltinib
03

Conditions

myelofibrosis (MF)

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