Trial intelligence / Profile preview

ctDNA Monitoring with Sacituzumab Tirumotecan in EGFR-Mutated NSCLC After EGFR-TKI Failure

ChiCTR2600115950Phase 4Not yet recruiting

Sponsor
Shaanxi Cancer Hospital
Start
Jan 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of sacituzumab tirumotecan in Non-small cell lung cancer (NS-NSCLC), sponsored by Shaanxi Cancer Hospital. Primary endpoint: Circulating tumor DNA (ctDNA). Planned start Jan 2026; status: not yet recruiting.

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Drugs

sacituzumab tirumotecan
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Conditions

Non-small cell lung cancer (NS-NSCLC)

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