Trial intelligence / Profile preview

Vebreltinib plus Andamertinib in EGFR-TKI–resistant MET-overexpressing NSCLC

ChiCTR2600117889Phase 2Not yet recruiting

Sponsor
Zhongshan Hospital, Fudan University
Start
Jan 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of vebreltinib and andamertinib in non-small cell lung cancer (NSCLC), sponsored by Zhongshan Hospital, Fudan University. Primary endpoints: Objective response rate and Progression-free survival. Planned start Jan 2026; status: not yet recruiting.

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Drugs

vebreltinibandamertinib
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Conditions

non-small cell lung cancer (NSCLC)

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