Trial intelligence / Profile preview

Platinum/taxoid-based neoadjuvant therapy with EGFR or PD-L1 antibody for recurrent resectable head and neck squamous cell carcinoma

ChiCTR2600118681Phase 2Not yet recruiting

Sponsor
Hunan Cancer Hospital
Start
Feb 2026
Modality
Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label, single-arm trial of nab-paclitaxel, cisplatin, pembrolizumab and cetuximab in head and neck squamous cell carcinoma (HNSCC), sponsored by Hunan Cancer Hospital. Primary endpoint: Overall survival at 2 years. Planned start Feb 2026; status: not yet recruiting.

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Drugs

nab-paclitaxelcisplatinpembrolizumabcetuximab
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Conditions

head and neck squamous cell carcinoma (HNSCC)

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