Trial intelligence / Profile preview

Azacitidine plus lisaftoclax in newly diagnosed higher-risk MDS (Phase II, single-arm)

ChiCTR2600118868Phase 2Not yet recruiting

Sponsor
First Affiliated Hospital, Zhejiang University School of Medicine
Start
Feb 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of azacitidine and lisaftoclax in myelodysplastic syndrome (MDS), sponsored by First Affiliated Hospital, Zhejiang University School of Medicine. Primary endpoint: Complete Response (CR). Planned start Feb 2026; status: not yet recruiting.

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Drugs

azacitidinelisaftoclax
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Conditions

myelodysplastic syndrome (MDS)

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