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Short-course radiotherapy + toripalimab + TAS-102 + regorafenib in later-line colorectal cancer

ChiCTR2600119059Phase 2Recruiting

Sponsor
Yantai Yuhuangding Hospital
Start
Feb 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of toripalimab, trifluridine + tipiracil and regorafenib in colorectal cancer (CRC), sponsored by Yantai Yuhuangding Hospital. Primary endpoint: Progression-free survival. Started Feb 2026; status: recruiting.

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Drugs

toripalimabtrifluridine + tipiracilregorafenib
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Conditions

colorectal cancer (CRC)

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