Trial intelligence / Profile preview

SeGVHD: Semaglutide plus standard prophylaxis to prevent acute GVHD after allo-HSCT

ChiCTR2600119595Phase 2Not yet recruiting

Sponsor
The Second Affiliated Hospital of Nanchang University
Start
Feb 2026
Modality
Recombinant Proteins and Enzymes, Peptides
Countries
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Overview

Phase 2, open-label, single-arm trial of semaglutide in Acute Graft-Versus-Host Disease (aGvHD) and hematopoietic malignancies, sponsored by The Second Affiliated Hospital of Nanchang University. Primary endpoint: Cumulative incidence of grade II–IV acute graft-versus-host disease within 100 days post-transplant. Planned start Feb 2026; status: not yet recruiting.

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Drugs

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Conditions

Acute Graft-Versus-Host Disease (aGvHD)hematopoietic malignancies

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