Trial intelligence / Profile preview

IGNITE-Larynx: Becotatug Vedotin + Pucotenlimab Neoadjuvant Therapy for Locally Advanced Laryngeal Cancer

ChiCTR2600120886Phase 2Not yet recruiting

Sponsor
Eye and ENT Hospital of Fudan University
Start
Mar 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of becotatug vedotin and pucotenlimab in laryngeal squamous cell carcinoma (LSCC), sponsored by Eye and ENT Hospital of Fudan University. Primary endpoint: One-year larynx preservation rate. Planned start Mar 2026; status: not yet recruiting.

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Drugs

becotatug vedotinpucotenlimab
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Conditions

laryngeal squamous cell carcinoma (LSCC)

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