Trial intelligence / Profile preview

VACAG regimen in elderly high-risk MDS and AML

ChiCTR2600120998Phase 2Not yet recruiting

Sponsor
Department of Hematology, Seventh Medical Center of Chinese PLA General Hospital
Start
Mar 2026
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of venetoclax, azacitidine, aclarubicin, cytarabine, daunorubicin and 1 more in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) (2 arms), sponsored by Department of Hematology, Seventh Medical Center of Chinese PLA General Hospital. Primary endpoints: CR/CRi rate within 2 treatment courses, MRD negativity rate within 2 treatment courses and 8 more. Planned start Mar 2026; status: not yet recruiting.

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Drugs

venetoclaxazacitidineaclarubicincytarabinedaunorubicin
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Conditions

myelodysplastic syndrome (MDS)acute myeloid leukemia (AML)

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