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Phase II trial of Cadonilimab (AK104) plus radiotherapy in ESCC after progression on PD-(L)1 therapy

ChiCTR2600121031Phase 2Completed

Sponsor
Sichuan Cancer Hospital & Institute
Start
Mar 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of cadonilimab in Esophageal Squamous Cell Carcinoma (ESCC), sponsored by Sichuan Cancer Hospital & Institute. Primary endpoints: Objective Response Rate (ORR) and Progression-Free Survival (PFS). Started Mar 2026; status: completed.

02

Drugs

cadonilimab
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Conditions

Esophageal Squamous Cell Carcinoma (ESCC)

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