Trial intelligence / Profile preview

High-dose hepatitis B vaccine plus pegylated interferon α-2b for functional cure in low HBsAg chronic hepatitis B

ChiCTR2600121635Phase 4Not yet recruiting

Sponsor
Xixi Hospital of Hangzhou
Start
Apr 2026
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
Countries
1
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Overview

Phase 4, open-label trial of Hepatitis B vaccine and peginterferon alfa-2b in Chronic Hepatitis B (CHB) (4 arms), sponsored by Xixi Hospital of Hangzhou. Primary endpoints: HBsAg clearance rate and Anti-HBs (HBsAb) seroconversion rate. Planned start Apr 2026; status: not yet recruiting.

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Drugs

Hepatitis B vaccinepeginterferon alfa-2b
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Conditions

Chronic Hepatitis B (CHB)

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