Trial intelligence / Profile preview

Gicaxitinib + selinexor for intermediate/high‑risk myelofibrosis

ChiCTR2600121951Phase 2Not yet recruiting

Sponsor
First Affiliated Hospital, Zhejiang University School of Medicine
Start
Apr 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of gicaxitinib and selinexor in myelofibrosis (MF), primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) and 1 more (2 arms), sponsored by First Affiliated Hospital, Zhejiang University School of Medicine. Primary endpoint: Spleen response rate at week 24. Planned start Apr 2026; status: not yet recruiting.

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Drugs

gicaxitinibselinexor
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Conditions

myelofibrosis (MF)primary myelofibrosis (PMF)post-polycythemia vera myelofibrosis (PPV-MF)post-essential thrombocythemia myelofibrosis (PET-MF)

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