Trial intelligence / Profile preview

DEX-I plus aflibercept vs aflibercept for diabetic macular edema

ChiCTR2600123418Phase 4Not yet recruiting

Sponsor
Shanghai General Hospital
Start
Apr 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, randomised trial in diabetic macular edema (DME) comparing Control: aflibercept monotherapy with aflibercept + dexamethasone intravitreal implant (2 arms). Primary endpoint: Change from baseline in central macular thickness at month 6. Planned start Apr 2026; status: not yet recruiting.

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Drugs

afliberceptdexamethasone
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Conditions

diabetic macular edema (DME)

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