Trial intelligence / Profile preview

Fruquintinib plus bemarituzumab vs fruquintinib as third-line therapy in metastatic colorectal cancer

ChiCTR2600123864Phase 2Not yet recruiting

Sponsor
Tai'an City Central Hospital
Start
Apr 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in metastatic colon cancer (mCRC) and colorectal cancer (CRC) comparing Fruquintinib + bemarituzumab with Fruquintinib (2 arms). Primary endpoint: Objective Response Rate. Planned start Apr 2026; status: not yet recruiting.

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Drugs

fruquintinibbemarituzumab
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Conditions

metastatic colon cancer (mCRC)colorectal cancer (CRC)

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