Trial intelligence / Profile preview

Liposomal vs hydrochloride bupivacaine for femoral nerve block after ACL reconstruction

ChiCTR2600124270Phase 4Not yet recruiting

Sponsor
First Affiliated Hospital of Xiamen University
Start
May 2026
Modality
Small Molecules, Nanoparticles → Drug Delivery Systems
Countries
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Overview

Phase 4, randomised, double-blind trial in postoperative pain comparing Experimental group: bupivacaine + liposomal bupivacaine with Control group: bupivacaine monotherapy (2 arms). Primary endpoint: Area under NRS score curve (AUC) at rest 12–72 hours postoperatively. Planned start May 2026; status: not yet recruiting.

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Drugs

bupivacaineliposomal bupivacaine
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Conditions

postoperative pain

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