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Phase II BEBT-109 in EGFR exon 20 insertion mutant NSCLC

ChiCTR2600124385Phase 2Completed

Sponsor
Guangdong Provincial People's Hospital
Start
May 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of BEBT-109 in non-small cell lung cancer (NSCLC) (2 cohorts), sponsored by Guangdong Provincial People's Hospital. Primary endpoints: Objective Response Rate and Progression-Free Survival. Started May 2026; status: completed.

02

Drugs

BEBT-109
03

Conditions

non-small cell lung cancer (NSCLC)

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