Trial intelligence / Profile preview

AI-081 PD-1/VEGF bispecific antibody in advanced solid tumors

ChiCTR2600125390Phase 2Recruiting

Sponsor
Guangdong Provincial People's Hospital
Start
May 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of cesalatamig in Nonhematologic neoplasms, colorectal cancer (CRC), non-small cell lung cancer (NSCLC) and 3 more (10 arms), sponsored by Guangdong Provincial People's Hospital. Primary endpoints: Part A: Maximum tolerated dose (MTD) or recommended Phase 2 dose (RP2D), Part A: Incidence of treatment-emergent adverse events (TEAEs) and treatment-related adverse events (TRAEs) and 2 more. Started May 2026; status: recruiting.

02

Drugs

cesalatamig
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Conditions

Nonhematologic neoplasmscolorectal cancer (CRC)non-small cell lung cancer (NSCLC)small cell lung cancer (SCLC)epithelial ovarian cancer (EOC)

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