Trial intelligence / Profile preview

LDRT + SBRT followed by Iparomlimab + Tuvonralimab as neoadjuvant therapy for locally advanced head and neck squamous cell carcinoma

ChiCTR2600125500Phase 4Not yet recruiting

Sponsor
First Affiliated Hospital of Xi'an Jiaotong University
Start
May 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, open-label, single-arm trial of iparomlimab and tuvonralimab in head and neck squamous cell carcinoma (HNSCC), sponsored by First Affiliated Hospital of Xi'an Jiaotong University. Primary endpoint: Pathologic Complete Response. Planned start May 2026; status: not yet recruiting.

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Drugs

iparomlimabtuvonralimab
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Conditions

head and neck squamous cell carcinoma (HNSCC)

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