Trial intelligence / Profile preview

Luvometinib Observational Cohort in Adult LCH and Histiocytic Neoplasms Using 68Ga-FAPI PET/CT

ChiCTR2600125932Phase 4Recruiting

Sponsor
West China Hospital of Sichuan University
Start
Jun 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of luvometinib in Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD) and histiocytic disease, sponsored by West China Hospital of Sichuan University. Primary endpoint: Objective response rate (ORR) based on PRC efficacy evaluation criteria. Started Jun 2026; status: recruiting.

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Drugs

luvometinib
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Conditions

Langerhans cell histiocytosis (LCH)Erdheim-Chester disease (ECD)histiocytic disease

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