Trial intelligence / Profile preview

Esketamine + dexmedetomidine vs sufentanil for PONV after TMJ fixation

ChiCTR2600127092Phase 4Not yet recruiting

Sponsor
Shanghai Ninth People's Hospital
Start
Jun 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised trial in postoperative nausea and vomiting (PONV), postoperative pain and temporomandibular disorder (TMD) comparing Esketamine + dexmedetomidine with Sufentanil (2 arms). Primary endpoint: Incidence of postoperative nausea and vomiting within 48 hours. Planned start Jun 2026; status: not yet recruiting.

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Drugs

esketaminedexmedetomidinesufentanil
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Conditions

postoperative nausea and vomiting (PONV)postoperative paintemporomandibular disorder (TMD)

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