Trial intelligence / Profile preview

Lenvatinib + Pembrolizumab With or Without Branched-Chain Amino Acids in Unresectable Hepatocellular Carcinoma

ChiCTR2600127139Phase 2Not yet recruiting

Sponsor
Huashan Hospital
Start
Jun 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in hepatocellular carcinoma (HCC) comparing Lenvatinib + Keytruda + BCAA with Lenvatinib + Keytruda (2 arms). Primary endpoint: Progression-free survival. Planned start Jun 2026; status: not yet recruiting.

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Drugs

lenvatinibpembrolizumabBranchamin
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Conditions

hepatocellular carcinoma (HCC)

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