Trial intelligence / Profile preview

Anlotinib + temozolomide vs bevacizumab + temozolomide in first recurrent high-grade glioma

ChiCTR2600127167Phase 4Not yet recruiting

Sponsor
Southwest Hospital of Army Medical University
Start
Jun 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial in glioma, glioblastoma (GBM) and anaplastic glioma comparing Anlotinib + temozolomide with Bevacizumab + temozolomide (2 arms). Primary endpoint: Progression-free survival. Planned start Jun 2026; status: not yet recruiting.

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Drugs

anlotinibtemozolomidebevacizumab
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Conditions

gliomaglioblastoma (GBM)anaplastic glioma

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