Trial intelligence / Profile preview

Short-course Sacituzumab Tirumotecan plus PD-1 inhibitors as first-line therapy in elderly PD-L1 positive driver-negative advanced NSCLC

ChiCTR2600127528Phase 2Not yet recruiting

Sponsor
Shanghai Geriatric Medical Center
Start
Jul 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of sacituzumab tirumotecan in non-small cell lung cancer (NSCLC), sponsored by Shanghai Geriatric Medical Center. Primary endpoint: Objective Response Rate (ORR). Planned start Jul 2026; status: not yet recruiting.

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Drugs

sacituzumab tirumotecan
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Conditions

non-small cell lung cancer (NSCLC)

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