Trial intelligence / Profile preview

Trastuzumab Rezetecan + Furmonertinib in EGFR-TKI–resistant HER2-overexpressing NSCLC

ChiCTR2600127967Phase 2Not yet recruiting

Sponsor
Second Affiliated Hospital of Zhejiang University School of Medicine
Start
Jul 2026
Modality
Small Molecules, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of trastuzumab rezetecan and furmonertinib in non-small cell lung cancer (NSCLC), sponsored by Second Affiliated Hospital of Zhejiang University School of Medicine. Primary endpoint: Objective response rate. Planned start Jul 2026; status: not yet recruiting.

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Drugs

trastuzumab rezetecanfurmonertinib
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Conditions

non-small cell lung cancer (NSCLC)

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