Trial intelligence / Profile preview

Ivarmacitinib + Camrelizumab + Fruquintinib in metastatic colorectal cancer after failure of second-line or later therapy

ChiCTR2600128602Phase 2Recruiting

Sponsor
Renmin Hospital of Wuhan University
Start
Jul 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of ivarmacitinib, camrelizumab and fruquintinib in colorectal cancer (CRC), sponsored by Renmin Hospital of Wuhan University. Primary endpoints: Objective response rate and Adverse events and serious adverse events. Started Jul 2026; status: recruiting.

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Drugs

ivarmacitinibcamrelizumabfruquintinib
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Conditions

colorectal cancer (CRC)

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