Trial intelligence / Profile preview

RC48 (disitamab vedotin) + toripalimab in HER2-expressing high-risk NMIBC

ChiCTR2600128773Phase 2Not yet recruiting

Sponsor
Chinese PLA General Hospital
Start
Jul 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of disitamab vedotin and toripalimab in transitional cell carcinoma of the bladder (TCC), sponsored by Chinese PLA General Hospital. Primary endpoint: Proportion of patients undergoing radical cystectomy at one year. Planned start Jul 2026; status: not yet recruiting.

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Drugs

disitamab vedotintoripalimab
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Conditions

transitional cell carcinoma of the bladder (TCC)

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