Trial intelligence / Profile preview

Hepatic arterial liposomal irinotecan + 5-fluorouracil/leucovorin for second-line colorectal liver metastases

ChiCTR2600130991Phase 2Not yet recruiting

Sponsor
Second Affiliated Hospital of Guangzhou Medical University
Start
Sep 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
1
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Overview

Phase 2, open-label, single-arm trial of nanoliposomal irinotecan, fluorouracil and folinic acid in colorectal cancer liver metastasis (CRLM), sponsored by Second Affiliated Hospital of Guangzhou Medical University. Primary endpoint: Objective response rate. Planned start Sep 2026; status: not yet recruiting.

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Drugs

nanoliposomal irinotecanfluorouracilfolinic acid
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Conditions

colorectal cancer liver metastasis (CRLM)

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