Trial intelligence / Profile preview

Cardonilizumab plus FOLFOX versus FOLFOX alone as neoadjuvant therapy for locally advanced pMMR/MSS colorectal cancer

ChiCTR2600131038Phase 2Recruiting

Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Start
Sep 2023
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of cadonilimab, folinic acid, fluorouracil and oxaliplatin in colorectal cancer (CRC) (2 arms), sponsored by Cancer Institute and Hospital, Chinese Academy of Medical Sciences. Primary endpoint: Pathological complete response rate. Started Sep 2023; status: recruiting.

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Drugs

cadonilimabfolinic acidfluorouraciloxaliplatin
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Conditions

colorectal cancer (CRC)

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