Trial intelligence / Profile preview

DAPA-LN trial of dapagliflozin added to maintenance therapy in biopsy-confirmed lupus nephritis

ChiCTR2600131121Phase 4Not yet recruiting

Sponsor
The Second Xiangya Hospital
Start
Sep 2026
Modality
Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial of dapagliflozin in lupus nephritis (LN) and systemic lupus erythematosus (SLE) (2 arms), sponsored by The Second Xiangya Hospital. Primary endpoints: Renal response rate at 52 weeks, Proportion with at least one predefined clinically significant AESI and 2 more. Planned start Sep 2026; status: not yet recruiting.

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Drugs

dapagliflozin
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Conditions

lupus nephritis (LN)systemic lupus erythematosus (SLE)

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