Trial intelligence / Profile preview

MRG003 plus pucotenlimab as neoadjuvant therapy for locally advanced oropharyngeal squamous cell carcinoma

ChiCTR2600131390Phase 2Recruiting

Sponsor
Sun Yat-sen University Cancer Center
Start
May 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of becotatug vedotin and pucotenlimab in oropharyngeal squamous cell carcinoma (OPSCC) (2 cohorts), sponsored by Sun Yat-sen University Cancer Center. Primary endpoint: Major pathological response. Started May 2026; status: recruiting.

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Drugs

becotatug vedotinpucotenlimab
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Conditions

oropharyngeal squamous cell carcinoma (OPSCC)

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