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Toripalimab plus cisplatin with single-dose versus fractionated nab-paclitaxel as neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma

ChiCTR2600131659Phase 2Recruiting

Sponsor
The First Affiliated Hospital of Zhengzhou University
Start
Oct 2025
Modality
Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised, open-label trial of toripalimab, paclitaxel and cisplatin in Esophageal Squamous Cell Carcinoma (ESCC) (2 arms), sponsored by The First Affiliated Hospital of Zhengzhou University. Primary endpoint: Disease-free survival. Started Oct 2025; status: recruiting.

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Drugs

toripalimabpaclitaxelcisplatin
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Conditions

Esophageal Squamous Cell Carcinoma (ESCC)

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