Trial intelligence / Profile preview

Idarubicin + subcutaneous cytarabine + G-CSF + lisaftoclax for MDS-IB2 and adult secondary or elderly AML

ChiCTR2600131661Phase 4Not yet recruiting

Sponsor
Ruijin Hospital
Start
Sep 2026
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of lisaftoclax, idarubicin, cytarabine and filgrastim in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), sponsored by Ruijin Hospital. Primary endpoint: Composite Complete Remission. Planned start Sep 2026; status: not yet recruiting.

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Drugs

lisaftoclaxidarubicincytarabinefilgrastim
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Conditions

myelodysplastic syndrome (MDS)acute myeloid leukemia (AML)

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