Trial intelligence / Profile preview

Digoxin + azacitidine + venetoclax in newly diagnosed elderly acute myeloid leukemia

ChiCTR2600131877Phase 2Not yet recruiting

Sponsor
First Affiliated Hospital of Chongqing Medical University
Start
Jan 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of digoxin, azacitidine and venetoclax in acute myeloid leukemia (AML), sponsored by First Affiliated Hospital of Chongqing Medical University. Primary endpoints: 3/6-month CR/CRi and Maximum tolerated dose. Planned start Jan 2026; status: not yet recruiting.

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Drugs

digoxinazacitidinevenetoclax
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Conditions

acute myeloid leukemia (AML)

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