Trial intelligence / Profile preview

16-hour fasting plus serplulimab and CAPEOX as neoadjuvant therapy for pMMR/MSS locally advanced mid-to-low rectal cancer

ChiCTR2600131976Phase 2Not yet recruiting

Sponsor
Second Affiliated Hospital of Zhejiang University School of Medicine
Start
Jun 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of serplulimab, capecitabine and oxaliplatin in rectal cancer, sponsored by Second Affiliated Hospital of Zhejiang University School of Medicine. Primary endpoint: pathological complete response. Planned start Jun 2026; status: not yet recruiting.

02

Drugs

serplulimabcapecitabineoxaliplatin
03

Conditions

rectal cancer

Beyond the preview

Go deeper on ChiCTR2600131976.

Study design, results and competitive context are available in the Gosset platform where reported.

Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

Bring the full picture into focus.

See how Gosset can support your research on ChiCTR2600131976.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call