Trial intelligence / Profile preview

ICI plus R-DA-EPOCH versus R-DA-EPOCH in untreated HIV-associated diffuse large B-cell lymphoma

ChiCTR2600132184Phase 4Not yet recruiting

Sponsor
Nanfang Hospital, Southern Medical University
Start
May 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label trial of tislelizumab, rituximab, etoposide, prednisone, vincristine and 2 more in diffuse large B-cell lymphoma (DLBCL) and human immunodeficiency virus infection (HIV) (2 arms), sponsored by Nanfang Hospital, Southern Medical University. Primary endpoints: Tumor imaging assessment results, Adverse events and 1 more. Planned start May 2026; status: not yet recruiting.

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Drugs

tislelizumabrituximabetoposideprednisonevincristine
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Conditions

diffuse large B-cell lymphoma (DLBCL)human immunodeficiency virus infection (HIV)

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