Trial intelligence / Profile preview

R2-CHOP versus R-CHOP as first-line treatment for elderly patients with HIV-associated diffuse large B-cell lymphoma

ChiCTR2600132819Phase 2Not yet recruiting

Sponsor
Nanfang Hospital, Southern Medical University
Start
Jan 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of lenalidomide, rituximab, cyclophosphamide, doxorubicin, vincristine and 1 more in diffuse large B-cell lymphoma (DLBCL) and human immunodeficiency virus infection (HIV) (2 arms), sponsored by Nanfang Hospital, Southern Medical University. Primary endpoints: Tumor imaging assessment results, Survival status and 1 more. Planned start Jan 2026; status: not yet recruiting.

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Drugs

lenalidomiderituximabcyclophosphamidedoxorubicinvincristine
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Conditions

diffuse large B-cell lymphoma (DLBCL)human immunodeficiency virus infection (HIV)

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