Trial intelligence / Profile preview

Phase II neoadjuvant iparomlimab + tuvonralimab with TCb for triple-negative breast cancer

ChiCTR2600133049Phase 2Not yet recruiting

Sponsor
First Hospital of China Medical University
Start
Sep 2026
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of iparomlimab, tuvonralimab, paclitaxel, docetaxel and carboplatin in triple-negative breast cancer (TNBC), sponsored by First Hospital of China Medical University. Primary endpoints: Pathological complete response rate and Disease-free survival. Planned start Sep 2026; status: not yet recruiting.

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Drugs

iparomlimabtuvonralimabpaclitaxeldocetaxelcarboplatin
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Conditions

triple-negative breast cancer (TNBC)

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