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Remimazolam versus dexmedetomidine and sevoflurane maintenance anesthesia during lower-limb tourniquet surgery
ChiCTR2600134033Phase 4Not yet recruiting
- Sponsor
- First Affiliated Hospital of Soochow University
- Start
- Apr 2026
- Modality
- Small Molecules
- Countries
- 1
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Overview
Phase 4, randomised, double-blind trial in ischemia-reperfusion injury (IRI) and oxidative stress comparing Dexmedetomidine group, Remimazolam group and Sevoflurane group (3 arms). Primary endpoint: Xanthine oxidase activity. Planned start Apr 2026; status: not yet recruiting.
02
Drugs
remimazolamdexmedetomidinesevoflurane
03
Conditions
ischemia-reperfusion injury (IRI)oxidative stress
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