Trial intelligence / Profile preview

Neoadjuvant radiochemotherapy plus QL1706 for locally advanced Siewert II gastroesophageal junction adenocarcinoma

ChiCTR2600134147Phase 2Recruiting

Sponsor
Anyang Cancer Hospital
Start
Oct 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of QL1706, oxaliplatin and tegafur-gimeracil-oteracil in gastroesophageal junction adenocarcinoma, sponsored by Anyang Cancer Hospital. Primary endpoint: Pathologic complete response rate. Started Oct 2025; status: recruiting.

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Drugs

QL1706oxaliplatintegafur-gimeracil-oteracil
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Conditions

gastroesophageal junction adenocarcinoma

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