Trial intelligence / Profile preview

NK-1 plus 5-HT3 inhibitor combination for prevention of nausea and vomiting during multi-week platinum chemotherapy

ChiCTR2600134502Phase 4Recruiting

Sponsor
Sir Run-Run Shaw Hospital
Start
Oct 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of fosrolapitant, palonosetron and dexamethasone in chemotherapy-induced nausea and vomiting (CINV), sponsored by Sir Run-Run Shaw Hospital. Primary endpoint: Complete response. Started Oct 2025; status: recruiting.

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Drugs

fosrolapitantpalonosetrondexamethasone
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Conditions

chemotherapy-induced nausea and vomiting (CINV)

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