Trial intelligence / Profile preview

Phase II neoadjuvant retlirafusp alfa plus SOX in TGFBR2-wild-type locally advanced gastric/GEJ adenocarcinoma

ChiCTR2600135037Phase 2Not yet recruiting

Sponsor
Xijing Hospital
Start
Nov 2026
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label, single-arm trial of retlirafusp alfa, oxaliplatin and tegafur in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma, sponsored by Xijing Hospital. Primary endpoint: Pathological complete response rate. Planned start Nov 2026; status: not yet recruiting.

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Drugs

retlirafusp alfaoxaliplatintegafur
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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