Trial intelligence / Profile preview

Retlirafusp alfa with concurrent long-course radiotherapy and XELOX for MSS locally advanced rectal cancer

ChiCTR2600135535Phase 4Not yet recruiting

Sponsor
The First Affiliated Hospital of Dalian Medical University
Start
Oct 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of retlirafusp alfa, capecitabine and oxaliplatin in rectal adenocarcinoma, sponsored by The First Affiliated Hospital of Dalian Medical University. Primary endpoint: Complete response rate. Planned start Oct 2026; status: not yet recruiting.

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Drugs

retlirafusp alfacapecitabineoxaliplatin
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Conditions

rectal adenocarcinoma

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