Trial intelligence / Profile preview

Vinorelbine versus vinorelbine + chidamide + toripalimab in advanced triple-negative breast cancer

ChiCTR2600135645Phase 2Not yet recruiting

Sponsor
Chinese PLA General Hospital
Start
Nov 2026
Modality
Small Molecules, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised, open-label trial in triple-negative breast cancer (TNBC) comparing Vinorelbine monotherapy arm with Vinorelbine plus chidamide and toripalimab arm (2 arms). Primary endpoints: Progression-free survival and Incidence and severity of treatment-related adverse events. Planned start Nov 2026; status: not yet recruiting.

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Drugs

vinorelbinetucidinostattoripalimab
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Conditions

triple-negative breast cancer (TNBC)

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