Trial intelligence / Profile preview

Zanubrutinib + rituximab versus bendamustine + rituximab in previously untreated transplant-ineligible mantle cell lymphoma

CTR20211594Phase 3Active

Sponsor
BeiGene
Start
Sep 2020
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in mantle cell lymphoma (MCL) comparing zanubrutinib + rituximab with bendamustine + rituximab (2 arms). Primary endpoint: Progression-free survival by independent central review. Started Sep 2020; status: active.

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Drugs

zanubrutinibrituximabbendamustine
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Conditions

mantle cell lymphoma (MCL)

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