Trial intelligence / Profile preview

ASC42 plus entecavir and Pegasys in chronic hepatitis B

CTR20212647Phase 2Completed

Sponsor
Ascletis Pharma Inc.
Start
Dec 2021
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, single-blind trial in Chronic Hepatitis B (CHB) comparing ASC42 + entecavir + Pegasys with Placebo + entecavir + Pegasys (2 arms). Primary endpoints: Change from baseline in serum HBV pgRNA and HBsAg levels at week 12 and week 24 of follow-up and Safety of ASC42 plus entecavir and peginterferon alfa-2a. Started Dec 2021; status: completed.

02

Drugs

asc42
03

Conditions

Chronic Hepatitis B (CHB)

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