Trial intelligence / Profile preview

fruquintinib + sintilimab versus axitinib or everolimus as second-line treatment for advanced renal cell carcinoma

CTR20222029Phase 3Completed

Sponsor
HUTCHMED
Start
Oct 2022
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of fruquintinib, sintilimab, axitinib and everolimus in renal cell carcinoma (RCC) (4 arms), sponsored by HUTCHMED. Primary endpoints: Progression-free survival and Objective response rate. Started Oct 2022; status: completed.

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Drugs

fruquintinibsintilimabaxitinibeverolimus
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Conditions

renal cell carcinoma (RCC)

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