Trial intelligence / Profile preview

RC108 plus toripalimab in c-Met-expressing advanced solid tumors

CTR20232828Phase 2Active

Sponsor
RemeGen
Start
Sep 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of RC108 and toripalimab in Nonhematologic neoplasms, adenoid cystic carcinoma (ACC), gastrointestinal cancer and 7 more (3 arms), sponsored by RemeGen. Primary endpoints: Dose-limiting toxicity, Safety and tolerability and 3 more. Started Sep 2023; status: active.

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Drugs

RC108toripalimab
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Conditions

Nonhematologic neoplasmsadenoid cystic carcinoma (ACC)gastrointestinal cancerhead and neck squamous cell carcinoma (HNSCC)Non-small cell lung cancer (NS-NSCLC)

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