Trial intelligence / Profile preview

Phase I/II open-label single-arm study of intravesical disitamab vedotin in HER2-expressing high-risk non-muscle-invasive bladder cancer

CTR20241297Phase 2Active

Sponsor
RemeGen
Start
Jun 2024
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of dapoxetine and disitamab vedotin in bladder cancer and non-muscle-invasive bladder cancer (NMIBC), sponsored by RemeGen. Primary endpoints: Dose-limiting toxicity, Maximum tolerated dose and 2 more. Started Jun 2024; status: active.

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Drugs

dapoxetinedisitamab vedotin
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Conditions

bladder cancernon-muscle-invasive bladder cancer (NMIBC)

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