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DeLLphi-305: Tarlatamab + durvalumab versus durvalumab maintenance in extensive-stage small cell lung cancer after first-line platinum-etoposide-durvalumab
CTR20241523Phase 3Active
- Sponsor
- Amgen
- Start
- Jun 2024
- Modality
- PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial in small cell lung cancer (SCLC) comparing Tarlatamab + durvalumab with Durvalumab (2 arms). Primary endpoint: Overall survival. Started Jun 2024; status: active.
02
Drugs
tarlatamabdurvalumab
03
Conditions
small cell lung cancer (SCLC)
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Competitive context
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